Oxymetholone

Oxymetholone (OXYMETOS), widely known as Anadrol or Anapolon, is a powerful synthetic anabolic steroid. It is a 17-alpha-alkylated compound derived from dihydrotestosterone (DHT). Originally, it was created to help treat medical conditions such as anemia, osteoporosis, and severe muscle loss in weak or undernourished patients. The drug received approval for human use from the U.S. Food and Drug Administration (FDA).

As medical science progressed, newer non-steroidal medications became available to treat these conditions more effectively. Because of this, oxymetholone gradually fell out of medical use, and by 1993, Syntex and several other manufacturers stopped producing it.

In terms of results, oxymetholone is very similar to methandienone. It delivers rapid muscle size increases along with a noticeable boost in strength. However, much of the fast weight gain comes from fluid retention, which may raise blood pressure during use.

Oxymetholone strongly increases red blood cell count and overall blood volume. This often causes an intense muscle pump during workouts. While some athletes enjoy this effect, it can also make training difficult, as muscles may feel tight and sore shortly after heavy sets.

Although oxymetholone is based on DHT and does not convert into estrogen through aromatization, it still displays strong estrogen-like effects. Because of this, aromatase inhibitors are ineffective for managing estrogen-related side effects. Only anti-estrogen medications can help reduce these reactions.

There has been speculation that oxymetholone’s estrogenic effects are linked to progesterone-like activity, similar to nandrolone compounds. However, scientific studies confirm that oxymetholone does not have progestogenic properties.